We research and treat muscle
disorders caused by immobilisation.
Muscle wasting and weakness are becoming increasingly prominent fields of study in medicine. In many cases, this is partly due to lack of exercise and inadequate training. The aim of the Network of Expertise for Immobilisation-induced Muscle Disorders (Kompetenz Netzwerk Immobilisationsbedingte Muskel Störungen; KNIMS) and its activities is to bring together active clinicians and scientists working on the relevant fundamental research and to offer a platform for discussing the diagnosis and treatment of immobilisation-induced muscle disorders.
Specific pathologies include:
... due to bedriddenness
especially among older patients, who require care as a result
... due to restraint
as a result of plaster casts or orthosis
... due to dysfunction
z.B. e.g. paraplegia
... in space
due to lack of gravity
Humans have evolved as a physically active species within Earth’s gravitational field. As a result, our bodies require a minimal level of muscle contraction and mechanical stress. Muscle activity below critical levels will lead to deconditioning and a loss of physical function that may go as far as to cause frailty and a loss of autonomy. As such, health problems and the loss of independence are major issues for society. KNIMS researchers are looking to identify the mechanisms underlying immobilisation-induced muscle disorders. The aim is to develop and apply improved, evidence-based and increasingly customised interventions to counteract such muscle disorders in different patient groups and across a range of settings.
Here is a patient talking about immobilisation in relation to the COVID-19 pandemic, from a report by the Tagesschau (German):